Ontology highlight
ABSTRACT:
SUBMITTER: Shah PT
PROVIDER: S-EPMC4923243 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Shah Preeya T PT Martin Rebecca R Yan Yanling Y Shapiro Joseph I JI Liu Jiang J
Frontiers in physiology 20160628
Na/K-ATPase signaling has been implicated in different physiological and pathophysiological conditions. Accumulating evidence indicates that oxidative stress not only regulates the Na/K-ATPase enzymatic activity, but also regulates its signaling and other functions. While cardiotonic steroids (CTS)-induced increase in reactive oxygen species (ROS) generation is an intermediate step in CTS-mediated Na/K-ATPase signaling, increase in ROS alone also stimulates Na/K-ATPase signaling. Based on litera ...[more]