Ontology highlight
ABSTRACT:
SUBMITTER: Pawar R
PROVIDER: S-EPMC4923501 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Pawar Rahul R Bali Omar Preet Singh OP Malhotra Bharat Kumar BK Lamba Gurpreet G
Stem cell investigation 20140320
Acute myeloid leukemia (AML) is a devastating hematologic malignancy that affects both older adults as well as children. Treatments available for AML largely depend on cytotoxic agents and often the only curative option is an allogeneic bone marrow transplant, an option limited to young persons and associated with high morbidity and mortality. There is an urgent need for the identification of new myeloid targets and an understanding of the key genetic mutations involved in disease progression an ...[more]