Ontology highlight
ABSTRACT:
SUBMITTER: Templeton AK
PROVIDER: S-EPMC4923513 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Templeton Amanda K AK Miyamoto Shinya S Babu Anish A Munshi Anupama A Ramesh Rajagopal R
Stem cell investigation 20140415
The identification of a subpopulation of tumor cells with stem cell-like characteristics first in hematological malignancies and later in solid tumors has emerged into a novel field of cancer research. It has been proposed that this aberrant population of cells now called "cancer stem cells" (CSCs) drives tumor initiation, progression, metastasis, recurrence, and drug resistance. CSCs have been shown to have the capacity of self-renewal and multipotency. Adopting strategies from the field of ste ...[more]