Ontology highlight
ABSTRACT:
SUBMITTER: Jacobson LA
PROVIDER: S-EPMC4925071 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Jacobson Lisa A LA Rane Shruti S McReynolds Lisa J LJ Steppan Diana A DA Chen Allen R AR Paz-Priel Ido I
Pediatrics 20160616 1
Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) is a rare, generally progressive, and potentially fatal syndrome of unclear etiology. The syndrome is characterized by normal development followed by a sudden, rapid hyperphagic weight gain beginning during the preschool period, hypothalamic dysfunction, and central hypoventilation, and is often accompanied by personality changes and developmental regression, leading to substantial morbidity ...[more]