Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021.
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ABSTRACT:
SUBMITTER: Ruan A
PROVIDER: S-EPMC4925249 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021.
Ruan Alexandra A Tobin Nicole H NH Mulligan Kathleen K Rollie Adrienne A Li Fan F Sleasman John J Aldrovandi Grace M GM
Journal of acquired immune deficiency syndromes (1999) 20160801 4
Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than females. Of 11 biomarkers assessed by sex and HIV-status, HIV-infected males had increased levels of soluble CD14 which inversely correlated with bone mineral content and bone mineral density measures, suggesting macrophage activation as a possible mechanism of differential bone loss. ...[more]
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