Ontology highlight
ABSTRACT:
SUBMITTER: Long M
PROVIDER: S-EPMC4926342 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Long Miao M Yang Shu-Hua SH Han Jian-Xin JX Li Peng P Zhang Yi Y Dong Shuang S Chen Xinliang X Guo Jiayi J Wang Jun J He Jian-Bin JB
International journal of molecular sciences 20160525 6
Although grape-seed proanthocyanidin extract (GSPE) demonstrates strong anti-oxidant activity, little research has been done to clearly reveal the protective effects on the hepatotoxicity caused by zearalenone (ZEN). This study is to explore the protective effect of GSPE on ZEN-induced oxidative damage of liver in Kunming mice and the possible protective molecular mechanism of GSPE. The results indicated that GSPE could greatly reduce the ZEN-induced increase of serum aspartate aminotransferase ...[more]