Ontology highlight
ABSTRACT:
SUBMITTER: Sun D
PROVIDER: S-EPMC4926459 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Sun Dayan D Li Bin B Qiu Ruyi R Fang Hezhi H Lyu Jianxin J
International journal of molecular sciences 20160621 6
Respiratory chain complexes are organized into large supercomplexes among which supercomplex In + IIIn + IVn is the only one that can directly transfer electrons from NADH to oxygen. Recently, it was reported that the formation of supercomplex In + IIIn + IVn in mice largely depends on their genetic background. However, in this study, we showed that the composition of supercomplex In + IIIn + IVn is well conserved in various mouse and human cell lines. Strikingly, we found that a minimal superco ...[more]