Ontology highlight
ABSTRACT:
SUBMITTER: Struyfs H
PROVIDER: S-EPMC4927852 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Struyfs Hanne H Van Hecke Wim W Veraart Jelle J Sijbers Jan J Slaets Sylvie S De Belder Maya M Wuyts Laura L Peters Benjamin B Sleegers Kristel K Robberecht Caroline C Van Broeckhoven Christine C De Belder Frank F Parizel Paul M PM Engelborghs Sebastiaan S
Journal of Alzheimer's disease : JAD 20150101 4
The purpose of this explorative study was to investigate whether diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) parameter changes are reliable measures of white matter integrity changes in Alzheimer's disease (AD) patients using a whole brain voxel-based analysis (VBA). Therefore, age- and gender-matched patients with mild cognitive impairment (MCI) due to AD (n = 18), dementia due to AD (n = 19), and age-matched cognitively healthy controls (n = 14) were prospectively inclu ...[more]