Exercise Increases and Browns Muscle Lipid in High-Fat Diet-Fed Mice.
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ABSTRACT:
SUBMITTER: Morton TL
PROVIDER: S-EPMC4928595 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
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Exercise Increases and Browns Muscle Lipid in High-Fat Diet-Fed Mice.
Morton Tiffany L TL Galior Kornelia K McGrath Cody C Wu Xin X Uzer Gunes G Uzer Guniz Bas GB Sen Buer B Xie Zhihui Z Tyson David D Rubin Janet J Styner Maya M
Frontiers in endocrinology 20160630
Muscle lipid increases with high-fat feeding and diabetes. In trained athletes, increased muscle lipid is not associated with insulin resistance, a phenomenon known as the athlete's paradox. To understand if exercise altered the phenotype of muscle lipid, female C57BL/6 mice fed CTL or high-fat diet (HFD for 6 or 18 weeks) were further divided into sedentary or exercising groups (CTL-E or HFD-E) with voluntary access to running wheels for the last 6 weeks of experiments, running 6 h/night. Diet ...[more]
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