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Estimations of dietary vitamin D requirements in black and white children.


ABSTRACT: The Institute of Medicine (IOM) dietary guidelines for vitamin D are based on limited pediatric data. Our objective was to estimate the dietary vitamin D requirements for maintaining serum 25-hydroxyvitamin D [25(OH)D] concentrations at the various IOM-considered thresholds of vitamin D status (12, 16, and 20?ng/ml) during fall and winter in children.Ninety-six healthy 8- to 14-y-old Pittsburgh-area black and white children enrolled in a randomized, placebo-controlled trial of vitamin D3 1,000 IU daily for 6 mo with baseline and 2-mo follow-up assessments completed during October through April were studied. Vitamin D intake from diet and study supplement adjusted for adherence and serum 25(OH)D were measured.The vitamin D intakes needed to maintain serum 25(OH)D concentrations at 12, 16, and 20?ng/ml in 90% of the children were 581, 1,062, and 1543 IU/day, respectively. The estimated vitamin D intakes needed to maintain serum 25(OH)D concentrations at 20?ng/ml in 97.5% of the children was 2,098 IU/day.Our data suggest that the current vitamin D recommended dietary allowance (RDA) (600 IU/day) is insufficient to cover the skeletal health needs of at least 50% of black and white children.

SUBMITTER: Rajakumar K 

PROVIDER: S-EPMC4929030 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature

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Estimations of dietary vitamin D requirements in black and white children.

Rajakumar Kumaravel K   Moore Charity G CG   Yabes Jonathan J   Olabopo Flora F   Haralam Mary Ann MA   Comer Diane D   Holick Michael F MF   Greenspan Susan L SL  

Pediatric research 20160309 1


<h4>Background</h4>The Institute of Medicine (IOM) dietary guidelines for vitamin D are based on limited pediatric data. Our objective was to estimate the dietary vitamin D requirements for maintaining serum 25-hydroxyvitamin D [25(OH)D] concentrations at the various IOM-considered thresholds of vitamin D status (12, 16, and 20 ng/ml) during fall and winter in children.<h4>Methods</h4>Ninety-six healthy 8- to 14-y-old Pittsburgh-area black and white children enrolled in a randomized, placebo-con  ...[more]

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