Ontology highlight
ABSTRACT:
SUBMITTER: Dinos GP
PROVIDER: S-EPMC4929435 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Dinos George P GP Athanassopoulos Constantinos M CM Missiri Dionissia A DA Giannopoulou Panagiota C PC Vlachogiannis Ioannis A IA Papadopoulos Georgios E GE Papaioannou Dionissios D Kalpaxis Dimitrios L DL
Antibiotics (Basel, Switzerland) 20160603 2
Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic activity by specifically inhibiting the bacterial protein synthesis. In certain but important cases, it also exhibits bactericidal activity, namely against the three most common causes of meningitis, Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis. ...[more]