Ontology highlight
ABSTRACT:
SUBMITTER: Palmer S
PROVIDER: S-EPMC4929632 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Palmer Scott S Litvinova Karina K Dunaev Andrey A Fleming Stewart S McGloin David D Nabi Ghulam G
Biomedical optics express 20160307 4
Muscle invasive urinary bladder cancer is one of the most lethal cancers and its detection at the time of transurethral resection remains limited and diagnostic methods are urgently needed. We have developed a muscle invasive transitional cell carcinoma (TCC) model of the bladder using porcine bladder scaffold and the human bladder cancer cell line 5637. The progression of implanted cancer cells to muscle invasion can be monitored by measuring changes in the spectrum of endogenous fluorophores s ...[more]