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The Diverse Structures and Functions of Surfactant Proteins.

ABSTRACT: Surface tension at liquid-air interfaces is a major barrier that needs to be surmounted by a wide range of organisms; surfactant and interfacially active proteins have evolved for this purpose. Although these proteins are essential for a variety of biological processes, our understanding of how they elicit their function has been limited. However, with the recent determination of high-resolution 3D structures of several examples, we have gained insight into the distinct shapes and mechanisms that have evolved to confer interfacial activity. It is now a matter of harnessing this information, and these systems, for biotechnological purposes.

SUBMITTER: Schor M

PROVIDER: S-EPMC4929970 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature

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The Diverse Structures and Functions of Surfactant Proteins.

Schor Marieke M Reid Jack L JL MacPhee Cait E CE Stanley-Wall Nicola R NR

Trends in biochemical sciences 20160527 7

Surface tension at liquid-air interfaces is a major barrier that needs to be surmounted by a wide range of organisms; surfactant and interfacially active proteins have evolved for this purpose. Although these proteins are essential for a variety of biological processes, our understanding of how they elicit their function has been limited. However, with the recent determination of high-resolution 3D structures of several examples, we have gained insight into the distinct shapes and mechanisms tha ...[more]

PMID: 27242193

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