Ontology highlight
ABSTRACT:
SUBMITTER: Cortinovis D
PROVIDER: S-EPMC4929979 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Cortinovis D D Abbate M M Bidoli P P Capici S S Canova S S
Ecancermedicalscience 20160623
Non-small-cell lung cancer is still considered a difficult disease to manage because of its aggressiveness and resistance to common therapies. Chemotherapy remains the gold standard in nearly 80% of lung cancers, but clinical outcomes are discouraging, and the impact on median overall survival (OS) barely reaches 12 months. At the end of the last century, the discovery of oncogene-driven tumours completely changed the therapeutic landscape in lung cancers, harbouring specific gene mutations/tran ...[more]