Ontology highlight
ABSTRACT:
SUBMITTER: Estcourt LJ
PROVIDER: S-EPMC4930145 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Estcourt Lise J LJ Stanworth Simon J SJ Hopewell Sally S Doree Carolyn C Trivella Marialena M Massey Edwin E
The Cochrane database of systematic reviews 20160429
<h4>Background</h4>Despite modern antimicrobials and supportive therapy bacterial and fungal infections are still major complications in people with prolonged disease-related or treatment-related neutropenia. Transfusions of granulocytes have a long history of usage in clinical practice to support and treat severe infection in high-risk groups of patients with neutropenia or neutrophil dysfunction. However, there is considerable current variability in therapeutic granulocyte transfusion practice ...[more]