Ontology highlight
ABSTRACT:
SUBMITTER: Conti G
PROVIDER: S-EPMC4930611 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Conti Giorgio G Ranieri Vito Marco VM Costa Roberta R Garratt Chris C Wighton Andrew A Spinazzola Giorgia G Urbino Rosario R Mascia Luciana L Ferrone Giuliano G Pohjanjousi Pasi P Ferreyra Gabriela G Antonelli Massimo M
Critical care (London, England) 20160702 1
<h4>Background</h4>Dexmedetomidine can be used for sedation of mechanically ventilated patients and has minor respiratory effects. The aim of this study was to compare the incidence of patient-ventilator dyssynchronies during sedation with dexmedetomidine or propofol.<h4>Methods</h4>We conducted a multicentre, prospective, open-label, randomised clinical trial, comparing dexmedetomidine with standard propofol sedation at three intensive care units of university hospitals in Italy. Twenty difficu ...[more]