Ontology highlight
ABSTRACT:
SUBMITTER: Guo J
PROVIDER: S-EPMC4930649 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Guo Juan J Ma Xiaohui X Cai Yuan Y Ma Ying Y Zhan Zhilai Z Zhou Yongjin J YJ Liu Wujun W Guan Mengxin M Yang Jian J Cui Guanghong G Kang Liping L Yang Lei L Shen Ye Y Tang Jinfu J Lin Huixin H Ma Xiaojing X Jin Baolong B Liu Zhenming Z Peters Reuben J RJ Zhao Zongbao K ZK Huang Luqi L
The New phytologist 20151218 2
Cytochromes P450 (CYPs) play a key role in generating the structural diversity of terpenoids, the largest group of plant natural products. However, functional characterization of CYPs has been challenging because of the expansive families found in plant genomes, diverse reactivity and inaccessibility of their substrates and products. Here we present the characterization of two CYPs, CYP76AH3 and CYP76AK1, which act sequentially to form a bifurcating pathway for the biosynthesis of tanshinones, t ...[more]