Ontology highlight
ABSTRACT:
SUBMITTER: Manuse S
PROVIDER: S-EPMC4931243 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Manuse Sylvie S Jean Nicolas L NL Guinot Mégane M Lavergne Jean-Pierre JP Laguri Cédric C Bougault Catherine M CM VanNieuwenhze Michael S MS Grangeasse Christophe C Simorre Jean-Pierre JP
Nature communications 20160627
Accurate placement of the bacterial division site is a prerequisite for the generation of two viable and identical daughter cells. In Streptococcus pneumoniae, the positive regulatory mechanism involving the membrane protein MapZ positions precisely the conserved cell division protein FtsZ at the cell centre. Here we characterize the structure of the extracellular domain of MapZ and show that it displays a bi-modular structure composed of two subdomains separated by a flexible serine-rich linker ...[more]