Ontology highlight
ABSTRACT:
SUBMITTER: Khan UW
PROVIDER: S-EPMC4931468 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Khan Uniza Wahid UW Øverli Øyvind Ø Hinkle Patricia M PM Pasha Farhan Ahmad FA Johansen Ida Beitnes IB Berget Ingunn I Silva Patricia I M PI Kittilsen Silje S Höglund Erik E Omholt Stig W SW Våge Dag Inge DI
Scientific reports 20160704
In many vertebrate species visible melanin-based pigmentation patterns correlate with high stress- and disease-resistance, but proximate mechanisms for this trait association remain enigmatic. Here we show that a missense mutation in a classical pigmentation gene, melanocyte stimulating hormone receptor (MC1R), is strongly associated with distinct differences in steroidogenic melanocortin 2 receptor (MC2R) mRNA expression between high- (HR) and low-responsive (LR) rainbow trout (Oncorhynchus myk ...[more]