Ontology highlight
ABSTRACT:
SUBMITTER: Wang SY
PROVIDER: S-EPMC4932196 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Wang Simon Yuan SY Lau Karen K Lai Keng-Po KP Zhang Jiang-Wen JW Tse Anna Chung-Kwan AC Li Jing-Woei JW Tong Yin Y Chan Ting-Fung TF Wong Chris Kong-Chu CK Chiu Jill Man-Ying JM Au Doris Wai-Ting DW Wong Alice Sze-Tsai AS Kong Richard Yuen-Chong RY Wu Rudolf Shiu-Sun RS
Nature communications 20160704
Hypoxia is amongst the most widespread and pressing problems in aquatic environments. Here we demonstrate that fish (Oryzias melastigma) exposed to hypoxia show reproductive impairments (retarded gonad development, decrease in sperm count and sperm motility) in F1 and F2 generations despite these progenies (and their germ cells) having never been exposed to hypoxia. We further show that the observed transgenerational reproductive impairments are associated with a differential methylation pattern ...[more]