Ontology highlight
ABSTRACT:
SUBMITTER: Ghosh A
PROVIDER: S-EPMC4932445 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
FEBS open bio 20160608 7
Escherichia coli HflX belongs to the widely distributed but poorly characterized HflX family of translation factor-related GTPases that is conserved from bacteria to humans. A 426-residue polypeptide that binds 50S ribosomes and has both GTPase and ATPase activities, HflX also exhibits autophosphorylation activity. We show that HflX(C), a C-terminal fragment of HflX, has an enhanced autophosphorylation activity compared to the full-length protein. Using a chemical stability assay and thin layer ...[more]