Ontology highlight
ABSTRACT:
SUBMITTER: Bondy-Denomy J
PROVIDER: S-EPMC4935067 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Bondy-Denomy Joseph J Garcia Bianca B Strum Scott S Du Mingjian M Rollins MaryClare F MF Hidalgo-Reyes Yurima Y Wiedenheft Blake B Maxwell Karen L KL Davidson Alan R AR
Nature 20150923 7571
The battle for survival between bacteria and the viruses that infect them (phages) has led to the evolution of many bacterial defence systems and phage-encoded antagonists of these systems. Clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-associated (cas) genes comprise an adaptive immune system that is one of the most widespread means by which bacteria defend themselves against phages. We identified the first examples of proteins produced by phages that inhibit ...[more]