Ontology highlight
ABSTRACT:
SUBMITTER: Phuah CL
PROVIDER: S-EPMC4936477 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Phuah Chia-Ling CL Raffeld Miriam R MR Ayres Alison M AM Gurol M Edip ME Viswanathan Anand A Greenberg Steven M SM Biffi Alessandro A Rosand Jonathan J Anderson Christopher D CD
Neurology. Genetics 20160623 4
<h4>Objective</h4>We sought to determine whether APOE genotype influences a previously observed decline in serum total cholesterol (TC) and low-density lipoprotein (LDL) levels preceding primary intracerebral hemorrhage (ICH), as a potential demonstration of nonamyloid mechanisms of APOE in ICH risk.<h4>Methods</h4>We performed a single-center retrospective longitudinal analysis using patients with known APOE genotype drawn from an ongoing cohort study of ICH. Serum lipid measurements for TC, tr ...[more]