Ontology highlight
ABSTRACT:
SUBMITTER: Singleton A
PROVIDER: S-EPMC4936485 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Singleton Andrew A Hardy John J
Neuron 20160601 6
Genetic discoveries underlie the majority of the current thinking in neurodegenerative disease. This work has been driven by the significant gains made in identifying causal mutations; however, the translation of genetic causes of disease into pathobiological understanding remains a challenge. The application of a second generation of genetics methods allows the dissection of moderate and mild genetic risk factors for disease. This requires new thinking in two key areas: what constitutes proof o ...[more]