Ontology highlight
ABSTRACT:
SUBMITTER: Shute JB
PROVIDER: S-EPMC4936504 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
NeuroImage. Clinical 20160625
Tourette syndrome (TS) is a neuropsychiatric disorder characterized by multiple motor and vocal tics. Deep brain stimulation (DBS) is an emerging therapy for severe cases of TS. We studied two patients with TS implanted with bilateral Medtronic Activa PC + S DBS devices, capable of chronic recordings, with depth leads in the thalamic centromedian-parafascicular complex (CM-PF) and subdural strips over the precentral gyrus. Low-frequency (1-10 Hz) CM-PF activity was observed during tics, as well ...[more]