Ontology highlight
ABSTRACT:
SUBMITTER: Niedzielska E
PROVIDER: S-EPMC4937091 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Niedzielska Ewa E Smaga Irena I Gawlik Maciej M Moniczewski Andrzej A Stankowicz Piotr P Pera Joanna J Filip Małgorzata M
Molecular neurobiology 20150722 6
The pathophysiologies of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD), are far from being fully explained. Oxidative stress (OS) has been proposed as one factor that plays a potential role in the pathogenesis of neurodegenerative disorders. Clinical and preclinical studies indicate that neurodegenerative diseases are characterized by higher levels of OS biomarkers and by lower levels of antioxidant defense bioma ...[more]