Goldmine integrates information placing genomic ranges into meaningful biological contexts.
Ontology highlight
ABSTRACT:
SUBMITTER: Bhasin JM
PROVIDER: S-EPMC4937336 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Publications
Goldmine integrates information placing genomic ranges into meaningful biological contexts.
Bhasin Jeffrey M JM Ting Angela H AH
Nucleic acids research 20160601 12
Bioinformatic analysis often produces large sets of genomic ranges that can be difficult to interpret in the absence of genomic context. Goldmine annotates genomic ranges from any source with gene model and feature contexts to facilitate global descriptions and candidate loci discovery. We demonstrate the value of genomic context by using Goldmine to elucidate context dynamics in transcription factor binding and to reveal differentially methylated regions (DMRs) with context-specific functional ...[more]
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