Ontology highlight
ABSTRACT:
SUBMITTER: Metzger MJ
PROVIDER: S-EPMC4939143 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Metzger Michael J MJ Villalba Antonio A Carballal María J MJ Iglesias David D Sherry James J Reinisch Carol C Muttray Annette F AF Baldwin Susan A SA Goff Stephen P SP
Nature 20160622 7609
Most cancers arise from oncogenic changes in the genomes of somatic cells, and while the cells may migrate by metastasis, they remain within that single individual. Natural transmission of cancer cells from one individual to another has been observed in two distinct cases in mammals (Tasmanian devils and dogs), but these are generally considered to be rare exceptions in nature. The discovery of transmissible cancer in soft-shell clams (Mya arenaria) suggested that this phenomenon might be more w ...[more]