Ontology highlight
ABSTRACT:
SUBMITTER: Huang X
PROVIDER: S-EPMC4939212 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Huang Xianping X Zhou Weihe W Zhang Yuefeng Y Liu Yong Y
BioMed research international 20160626
Lung cancer has been the most common cancer and the main cause of cancer-related deaths worldwide for several decades. PTGR1 (prostaglandin reductase 1), as a bifunctional enzyme, has been involved in the occurrence and progression of cancer. However, its impact on human lung cancer is rarely reported. In this study, we found that PTGR1 was overexpressed in lung cancer based on the analyses of Oncomine. Moreover, lentivirus-mediated shRNA knockdown of PTGR1 reduced cell viability in human lung c ...[more]