Ontology highlight
ABSTRACT:
SUBMITTER: Zhao GF
PROVIDER: S-EPMC4940108 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Molecular medicine reports 20160527 2
In silico drug design using virtual screening, absorption, distribution, metabolism and excretion (ADME)/Tox data analysis, automated docking and molecular dynamics simulations for the determination of lead compounds for further in vitro analysis is a cost effective strategy. The present study used this strategy to discover novel lead compounds from an in-house database of Traditional Chinese Medicinal (TCM) compounds against epithelial growth factor receptor (EGFR) protein for targeting non-sma ...[more]