Dataset Information

A pilot study on using chlorine dioxide gas for disinfection of gastrointestinal endoscopes.

ABSTRACT:

Objectives

This pilot study of employing chlorine dioxide (CD) gas to disinfect gastrointestinal endoscopes was conducted to meet the expectations of many endoscopy units in China for a high-efficiency and low-cost disinfectant.

Methods

An experimental prototype with an active circulation mode was designed to use CD gas to disinfect gastrointestinal endoscopes. One type of testing device composed of polytetrafluoroethylene (PTFE) tubes (2 m long, inner diameter 1 mm) and bacterial carrier containers was used to simulate the channel of the endoscope. PTFE bacterial carriers inoculated with Bacillus atrophaeus with or without organic burden were used to evaluate the sporicidal activity of CD gas. Factors including exposure dosage, relative humidity (RH), and flow rate (FR) influencing the disinfection effect of CD gas were investigated. Moreover, an autoptic disinfecting test on eight real gastrointestinal endoscopes after clinical use was performed using the experimental prototype.

Results

RH, exposure dosage, organic burden, and the FR through the channel significantly (P<0.05) affected the disinfection efficacy of CD gas for a long and narrow lumen. The log reduction increased as FR decreased. Treatment with 4 mg/L CD gas for 30 min at 0.8 L/min FR and 75% RH, resulted in complete inactivation of spores. Furthermore, all eight endoscopes with a maximum colony-forming unit of 915 were completely disinfected. The cost was only 3 CNY (0.46 USD) for each endoscope.

Conclusions

The methods and results reported in this study could provide a basis for further studies on using CD gas for the disinfection of endoscopes.

SUBMITTER: Yi Y

PROVIDER: S-EPMC4940628 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature

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Publications

A pilot study on using chlorine dioxide gas for disinfection of gastrointestinal endoscopes.

Yi Ying Y Hao Li-Mei LM Ma Shu-Ren SR Wu Jin-Hui JH Wang Tao T Lin Song S Zhang Zong-Xing ZX Qi Jian-Cheng JC

Journal of Zhejiang University. Science. B 20160701 7

<h4>Objectives</h4>This pilot study of employing chlorine dioxide (CD) gas to disinfect gastrointestinal endoscopes was conducted to meet the expectations of many endoscopy units in China for a high-efficiency and low-cost disinfectant.<h4>Methods</h4>An experimental prototype with an active circulation mode was designed to use CD gas to disinfect gastrointestinal endoscopes. One type of testing device composed of polytetrafluoroethylene (PTFE) tubes (2 m long, inner diameter 1 mm) and bacterial ...[more]

PMID: 27381729

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Dataset Information

A pilot study on using chlorine dioxide gas for disinfection of gastrointestinal endoscopes.

Objectives

Methods

Results

Conclusions

Publications

A pilot study on using chlorine dioxide gas for disinfection of gastrointestinal endoscopes.

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