Ontology highlight
ABSTRACT:
SUBMITTER: Pera T
PROVIDER: S-EPMC4942340 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Pera Tonio T Penn Raymond B RB
Pharmacology & therapeutics 20160423
Despite over 50years of inhaled beta-agonists and corticosteroids as the default management or rescue drugs for asthma, recent research suggests that new therapeutic options are likely to emerge. This belief stems from both an improved understanding of what causes and regulates airway smooth muscle (ASM) contraction, and the identification of new targets whose inhibition or activation can relax ASM. In this review we discuss the recent findings that provide new insight into ASM contractile regul ...[more]