The efficacy and safety of rituximab in treating childhood nephrotic syndrome: an Italian perspective.
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ABSTRACT:
SUBMITTER: Maratea D
PROVIDER: S-EPMC4943005 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Publications
The efficacy and safety of rituximab in treating childhood nephrotic syndrome: an Italian perspective.
Maratea Dario D Bettio Monica M Corti Maria Grazia MG Montini Giovanni G Venturini Francesca F
Italian journal of pediatrics 20160712 1
<h4>Background</h4>Nephrotic syndrome is a disorder characterized by proteinuria, hypoalbuminemia and dyslipidemia. Low-dose alternate-day steroid regimen is the standard of care. In case of relapse or significant adverse events, steroid-sparing agents may be used. This analysis was aimed at assessing the efficacy and safety of rituximab for the treatment of children with nephrotic syndrome.<h4>Results</h4>Four studies were included in the final meta-analysis. The end-point of our analysis was t ...[more]
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