Ontology highlight
ABSTRACT:
SUBMITTER: Dash BC
PROVIDER: S-EPMC4945325 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Stem cell reports 20160701 1
There is an urgent need for an efficient approach to obtain a large-scale and renewable source of functional human vascular smooth muscle cells (VSMCs) to establish robust, patient-specific tissue model systems for studying the pathogenesis of vascular disease, and for developing novel therapeutic interventions. Here, we have derived a large quantity of highly enriched functional VSMCs from human induced pluripotent stem cells (hiPSC-VSMCs). Furthermore, we have engineered 3D tissue rings from h ...[more]