Ontology highlight
ABSTRACT:
SUBMITTER: Wakabayashi T
PROVIDER: S-EPMC4946934 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Wakabayashi Tamami T Hidaka Ryo R Fujimaki Shin S Asashima Makoto M Kuwabara Tomoko T
The Journal of biological chemistry 20160520 29
Diabetes is associated with impaired cognitive function. Streptozotocin (STZ)-induced diabetic rats exhibit a loss of neurogenesis and deficits in behavioral tasks involving spatial learning and memory; thus, impaired adult hippocampal neurogenesis may contribute to diabetes-associated cognitive deficits. Recent studies have demonstrated that adult neurogenesis generally occurs in the dentate gyrus of the hippocampus, the subventricular zone, and the olfactory bulbs (OB) and is defective in pati ...[more]