Ontology highlight
ABSTRACT:
SUBMITTER: Blech-Hermoni Y
PROVIDER: S-EPMC4946975 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Developmental dynamics : an official publication of the American Association of Anatomists 20160531 8
<h4>Background</h4>CUG-BP, Elav-like family member 1 (CELF1) is a multifunctional RNA binding protein found in a variety of adult and embryonic tissues. In the heart, CELF1 is found exclusively in the myocardium. However, the roles of CELF1 during cardiac development have not been completely elucidated.<h4>Results</h4>Myofibrillar organization is disrupted and proliferation is reduced following knockdown of CELF1 in cultured chicken primary embryonic cardiomyocytes. In vivo knockdown of Celf1 in ...[more]