Ontology highlight
ABSTRACT:
SUBMITTER: Patel A
PROVIDER: S-EPMC4947437 | biostudies-literature | 2016 Sep-Oct
REPOSITORIES: biostudies-literature
Biotechnology advances 20160430 5
In recent years, there has been great progress in the understanding of tumor biology and its surrounding microenvironment. Solid tumors create regions with low oxygen levels, generally termed as hypoxic regions. These hypoxic areas offer a tremendous opportunity to develop targeted therapies. Hypoxia is not a random by-product of the cellular milieu due to uncontrolled tumor growth; rather it is a constantly evolving participant in overall tumor growth and fate. This article reviews current tren ...[more]