Factoring in Factor VIII With Acute Ischemic Stroke.
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ABSTRACT:
SUBMITTER: Siegler JE
PROVIDER: S-EPMC4948295 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Publications
Factoring in Factor VIII With Acute Ischemic Stroke.
Siegler James E JE Samai Alyana A Albright Karen C KC Boehme Amelia K AK Martin-Schild Sheryl S
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20150210 7
There is growing research interest into the etiologies of cryptogenic stroke, in particular as it relates to hypercoagulable states. An elevation in serum levels of the procoagulant factor VIII is recognized as one such culprit of occult cerebral infarctions. It is the objective of the present review to summarize the molecular role of factor VIII in thrombogenesis and its clinical use in the diagnosis and prognosis of acute ischemic stroke. We also discuss the utility of screening for serum fact ...[more]
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