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Project QUIT (Quit Using Drugs Intervention Trial): a randomized controlled trial of a primary care-based multi-component brief intervention to reduce risky drug use.


ABSTRACT: To assess the effect of a multi-component primary care delivered brief intervention for reducing risky psychoactive drug use (RDU) among patients identified by screening.Multicenter single-blind two-arm randomized controlled trial of patients enrolled from February 2011 to November 2012 with 3-month follow-up. Randomization and allocation to trial group were computer-generated.Primary care waiting rooms of five federally qualified health centers in Los Angeles County (LAC), USA.A total of 334 adult primary care patients (171 intervention; 163 control) with RDU scores (4-26) on the World Health Organization (WHO) Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) self-administered on tablet computers. 261 (78%) completed follow-up. Mean age was 41.7?years; 62.9% were male; 37.7% were Caucasian.Intervention patients received brief (typically 3-4 minutes) clinician advice to quit/reduce their drug use reinforced by a video doctor message, health education booklet and up to two 20-30-minute follow-up telephone drug use coaching sessions. Controls received usual care and cancer screening information. Primary outcome was patient self-reported use of highest scoring drug (HSD) at follow-up.Intervention and control patients reported equivalent baseline HSD use at 3-month follow-up. After adjustment for covariates, in the complete sample linear regression model, intervention patients used their HSD on 3.5 fewer days in the previous month relative to controls (P<0.001), and in the completed sample model, intervention patients used their HSD 2.2 fewer days than controls (P?

SUBMITTER: Gelberg L 

PROVIDER: S-EPMC4948983 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Project QUIT (Quit Using Drugs Intervention Trial): a randomized controlled trial of a primary care-based multi-component brief intervention to reduce risky drug use.

Gelberg Lillian L   Andersen Ronald M RM   Afifi Abdelmonem A AA   Leake Barbara D BD   Arangua Lisa L   Vahidi Mani M   Singleton Kyle K   Yacenda-Murphy Julia J   Shoptaw Steve S   Fleming Michael F MF   Baumeister Sebastian E SE  

Addiction (Abingdon, England) 20151101 11


<h4>Aims</h4>To assess the effect of a multi-component primary care delivered brief intervention for reducing risky psychoactive drug use (RDU) among patients identified by screening.<h4>Design</h4>Multicenter single-blind two-arm randomized controlled trial of patients enrolled from February 2011 to November 2012 with 3-month follow-up. Randomization and allocation to trial group were computer-generated.<h4>Setting</h4>Primary care waiting rooms of five federally qualified health centers in Los  ...[more]

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