Ontology highlight
ABSTRACT:
SUBMITTER: Taneja N
PROVIDER: S-EPMC4949487 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Taneja Nilay N Fenix Aidan M AM Rathbun Lindsay L Millis Bryan A BA Tyska Matthew J MJ Hehnly Heidi H Burnette Dylan T DT
Scientific reports 20160719
The geometry of the cleavage furrow during mitosis is often asymmetric in vivo and plays a critical role in stem cell differentiation and the relative positioning of daughter cells during development. Early observations of adhesive cell lines revealed asymmetry in the shape of the cleavage furrow, where the bottom (i.e., substrate attached side) of the cleavage furrow ingressed less than the top (i.e., unattached side). This data suggested substrate attachment could be regulating furrow ingressi ...[more]