Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data.
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ABSTRACT:
SUBMITTER: Diendorfer AB
PROVIDER: S-EPMC4949662 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Publications
Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data.
Diendorfer Andreas B AB Hackl Matthias M Klanert Gerald G Jadhav Vaibhav V Reithofer Manuel M Stiefel Fabian F Hesse Friedemann F Grillari Johannes J Borth Nicole N
Biotechnology and bioengineering 20150408 7
MicroRNAs are small non-coding RNAs that play a critical role in post-transcriptional control of gene expression. Recent publications of genomic sequencing data from the Chinese Hamster (CGR) and Chinese hamster ovary (CHO) cells provide new tools for the discovery of novel miRNAs in this important production system. Version 20 of the miRNA registry miRBase contains 307 mature miRNAs and 200 precursor sequences for CGR/CHO. We searched for evolutionary conserved miRNAs from miRBase v20 in recent ...[more]
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