Ontology highlight
ABSTRACT:
SUBMITTER: Gokce O
PROVIDER: S-EPMC4951190 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Gökçe Onur O Bonhoeffer Tobias T Scheuss Volker V
eLife 20160719
The spatial organization of synaptic inputs on the dendritic tree of cortical neurons plays a major role for dendritic integration and neural computations, yet, remarkably little is known about it. We mapped the spatial organization of glutamatergic synapses between layer 5 pyramidal cells by combining optogenetics and 2-photon calcium imaging in mouse neocortical slices. To mathematically characterize the organization of inputs we developed an approach based on combinatorial analysis of the lik ...[more]