A network-based method for identifying prognostic gene modules in lung squamous carcinoma.
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ABSTRACT:
SUBMITTER: Feng L
PROVIDER: S-EPMC4951267 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
A network-based method for identifying prognostic gene modules in lung squamous carcinoma.
Feng Lin L Tong Run R Liu Xiaohong X Zhang Kaitai K Wang Guiqi G Zhang Lei L An Ning N Cheng Shujun S
Oncotarget 20160401 14
Similarities in gene expression between both developing embryonic and precancerous tissues and cancer tissues may help identify much-needed biomarkers and therapeutic targets in lung squamous carcinoma. In this study, human lung samples representing ten successive time points, from embryonic development to carcinogenesis, were used to construct global gene expression profiles. Differentially expressed genes with similar expression in precancerous and cancer samples were identified. Using a netwo ...[more]
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