Ontology highlight
ABSTRACT:
SUBMITTER: Pham Thanh D
PROVIDER: S-EPMC4954929 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Pham Thanh Duy D Thanh Tuyen Ha H Nguyen Thi Nguyen To T Chung The Hao H Wick Ryan R RR Thwaites Guy E GE Baker Stephen S Holt Kathryn E KE
The Journal of antimicrobial chemotherapy 20160530 8
<h4>Objectives</h4>The objective of this study was to assess the presence of mcr-1 in Shigella sonnei isolated in Vietnam.<h4>Methods</h4>WGS data were analysed for the presence of the mcr-1 gene sequence. The association of mcr-1 with a plasmid was assessed by PCR and by conjugation.<h4>Results</h4>Through genome sequencing we identified a plasmid-associated inactive form of mcr-1 in a 2008 Vietnamese isolate of Shigella sonnei. The plasmid was conjugated into Escherichia coli and mcr-1 was act ...[more]