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Hyperthermia using nanoparticles--Promises and pitfalls.


ABSTRACT: An ever-increasing body of literature affirms the physical and biological basis for sensitisation of tumours to conventional therapies such as chemotherapy and radiation therapy by mild temperature hyperthermia. This knowledge has fuelled the efforts to attain, maintain, measure and monitor temperature via technological advances. A relatively new entrant in the field of hyperthermia is nanotechnology which capitalises on locally injected or systemically administered nanoparticles that are activated by extrinsic energy sources to generate heat. This review describes the kinds of nanoparticles available for hyperthermia generation, their activation sources, their characteristics, and the unique opportunities and challenges with nanoparticle-mediated hyperthermia.

SUBMITTER: Kaur P 

PROVIDER: S-EPMC4955578 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Hyperthermia using nanoparticles--Promises and pitfalls.

Kaur Punit P   Aliru Maureen L ML   Chadha Awalpreet S AS   Asea Alexzander A   Krishnan Sunil S  

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20160112 1


An ever-increasing body of literature affirms the physical and biological basis for sensitisation of tumours to conventional therapies such as chemotherapy and radiation therapy by mild temperature hyperthermia. This knowledge has fuelled the efforts to attain, maintain, measure and monitor temperature via technological advances. A relatively new entrant in the field of hyperthermia is nanotechnology which capitalises on locally injected or systemically administered nanoparticles that are activa  ...[more]

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