Ontology highlight
ABSTRACT:
SUBMITTER: Henrikson NB
PROVIDER: S-EPMC4955831 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Henrikson Nora B NB Webber Elizabeth M EM Goddard Katrina A KA Scrol Aaron A Piper Margaret M Williams Marc S MS Zallen Doris T DT Calonge Ned N Ganiats Theodore G TG Janssens A Cecile J W AC Zauber Ann A Lansdorp-Vogelaar Iris I van Ballegooijen Marjolein M Whitlock Evelyn P EP
Genetics in medicine : official journal of the American College of Medical Genetics 20150115 9
<h4>Purpose</h4>Family history of colorectal cancer (CRC) is a known risk factor for CRC and encompasses both genetic and shared environmental risks.<h4>Methods</h4>We conducted a systematic review to estimate the impact of family history on the natural history of CRC and adherence to screening.<h4>Results</h4>We found high heterogeneity in family-history definitions, the most common definition being one or more first-degree relatives. The prevalence of family history may be lower than the commo ...[more]