Ontology highlight
ABSTRACT:
SUBMITTER: Yuan F
PROVIDER: S-EPMC4957080 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Yuan Fang F Sun Ruifen R Li Lijuan L Jin Bo B Wang Yanyun Y Liang Yundan Y Che Guanglu G Gao Linbo L Zhang Lin L
Scientific reports 20160722
MicroRNA (miR)-143 and miR-145 have been identified as molecular regulators in cell proliferation, cell growth, clone formation, apoptosis, cell cycle, invasion, and migration. We previously found that rs353292 in the flanking region of miR-143/145 showed a high frequency in patients with colorectal cancer (CRC). To identify whether the rs353292 polymorphism is a risk factor for CRC, we conducted this study with larger samples. A total of 809 patients with CRC and 1005 gender matched controls we ...[more]