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Additive- and Metal-Free, Predictably 1,2- and 1,3-Regioselective, Photoinduced Dual C-H/C-X Borylation of Haloarenes.

ABSTRACT: We report herein a simple, additive- and metal-free, photoinduced, dual C-H/C-X borylation of chloro-, bromo-, and iodoarenes. The reaction produces 1,2- and 1,3-diborylarenes on gram scales under batch and continuous flow conditions. The regioselectivity of the dual C-H/C-X borylation is determined by the solvent and the substituents in the parent haloarenes.

SUBMITTER: Mfuh AM

PROVIDER: S-EPMC4958914 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature

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Additive- and Metal-Free, Predictably 1,2- and 1,3-Regioselective, Photoinduced Dual C-H/C-X Borylation of Haloarenes.

Mfuh Adelphe M AM Nguyen Vu T VT Chhetri Bhuwan B Burch Jessica E JE Doyle John D JD Nesterov Vladimir N VN Arman Hadi D HD Larionov Oleg V OV

Journal of the American Chemical Society 20160701 27

We report herein a simple, additive- and metal-free, photoinduced, dual C-H/C-X borylation of chloro-, bromo-, and iodoarenes. The reaction produces 1,2- and 1,3-diborylarenes on gram scales under batch and continuous flow conditions. The regioselectivity of the dual C-H/C-X borylation is determined by the solvent and the substituents in the parent haloarenes. ...[more]

PMID: 27347688

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