Ontology highlight
ABSTRACT:
SUBMITTER: Gupta S
PROVIDER: S-EPMC4958977 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Gupta Sneha S Biswas Arijit A Akhter Mohammad Suhail MS Krettler Christoph C Reinhart Christoph C Dodt Johannes J Reuter Andreas A Philippou Helen H Ivaskevicius Vytautas V Oldenburg Johannes J
Scientific reports 20160725
The activation and regulation of coagulation Factor XIII (FXIII) protein has been the subject of active research for the past three decades. Although discrete evidence exists on various aspects of FXIII activation and regulation a combinatorial structure/functional view in this regard is lacking. In this study, we present results of a structure/function study of the functional chain of events for FXIII. Our study shows how subtle chronological submolecular changes within calcium binding sites ca ...[more]