Ontology highlight
ABSTRACT:
SUBMITTER: Lipton RB
PROVIDER: S-EPMC4959035 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Lipton Richard B RB Rosen Noah L NL Ailani Jessica J DeGryse Ronald E RE Gillard Patrick J PJ Varon Sepideh F SF
Cephalalgia : an international journal of headache 20160610 9
<h4>Background</h4>Chronic migraine (CM) is associated with high impact and reduced health-related quality of life (HRQoL).<h4>Methods</h4>Patients with CM from PREEMPT (Phase 3 REsearch Evaluating Migraine Prophylaxis Therapy) were randomized (1:1) to receive onabotulinumtoxinA or placebo for two 12-week cycles in the double-blind (DB) phase, followed by three 12-week cycles of open-label (OL) onabotulinumtoxinA (onabotulinumtoxinA/onabotulinumtoxinA (O/O) and placebo/onabotulinumtoxinA (P/O) g ...[more]